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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but they are uncommon In this particular malignancy compared to other lymphoid neoplasms. CHD2 is mutated in five% of CLL and 7% of MBL.75 The histone methyltransferase SETD2 and ARID1A are mutated in a little proportion of clients. Of Notice, MYD88 mutatio